Daniel Andrade da Cunha

Bio
Daniel Andrade da Cunha is a Research Director at Flen Health and a molecular and cellular biologist with over 20 years of experience in academia and the biopharmaceutical industry. He has led multidisciplinary research teams in drug discovery, target identification, assay development and biomarker strategy across therapeutic areas including wound healing, oncology and diabetes. Daniel has authored 45 peer‑reviewed publications and is recognized for translating complex omics data into impactful therapeutic innovation.

Summary
Infection is a current critical challenge in burn wounds. We introduce an enzyme‑based antimicrobial approach as a resistance‑free alternative to conventional topical treatments. Focusing on Flaminal®, an enzyme alginogel, we outline its dual action in effective exudate management and autolytic debridement, while delivering broad‑spectrum antimicrobial activity against bacteria and fungi. The underlying glucose oxidase–lactoperoxidase enzyme system, inspired by the innate immune system, demonstrates potent microbial killing without cytotoxicity and without inducing microbial resistance, even after repeated exposure. Clinical and experimental data support its efficacy in burn wound management and highlight its potential role in addressing antimicrobial resistance.